Optoretinography refers generally to the non-invasive, optical imaging of light-induced functional activity in the retina and draws a parallel to the classical electroretinogram. As a non-contact, all-optical probe of cellular-scale retinal function, it provides unprecedented access to the living eye, both in health and disease. While optical recordings of neural cells can be traced back more than 50 years ago, it is only very recently that the technology has evolved towards in vivo human translation.
In this webinar hosted by the Color Technical Group, Ramkumar Sabesan from the University of Washington will first provide a historical overview of probing neural activity with light. The webinar will then review the fundamental technological advances in retinal imaging that have led to the current state-of-the-art of optoretinography, including its application to color vision and clinical translation. Finally, the challenges – technological, translational and mechanistic – that need to be overcome for widespread use and potential pathways of overcoming them will be discussed.
Subject Matter Level: Intermediate - Assumes basic knowledge of the topic
What You Will Learn:
• Fundamentals of optical technologies that underlie optoretinography (ORG)
• The underlying biophysical and physiological mechanisms of ORG
• Applications of ORG to basic vision science and clinical research
Who Should Attend:
• Trainees (undergraduate, graduate students and postdocs) interested in vision, optics and clinical science
• Optical engineers/physicists
• Vision scientists
• Clinicians and clinician scientists