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Big Data and Hyperspectral Imaging Uncover Hidden Regularities of Native Colours and Patterns in Cells and Tissues
In this webinar hosted by the OSA Laser Systems Technical Group, Ewa Goldys, Deputy Director of the Australian Research Council Centre of Excellence for Nanoscale Biophotonics, will discuss next-generation technologies developed at the Centre for probing, imaging and interacting with the living systems. These address the key challenges of ultrasensitive detection of key analytes in real complex environments and molecular complexity, and they support both novel therapies and diagnostics.

By retooling a microscope with modern light emitting diodes and powerful software, they have been able to exploit a commonly ignored trait inherent to all cells: their individual colour expression and its patterns. The hyperspectral imaging technique pioneered by their team allows precise quantification of the native fluorescent colour of cells and tissues. Through this approach, and by using the “big data” approach and the high processing speeds of modern computers, we are now able to non-invasively image aspects of biomolecular composition of cells and tissues including those relevant to metabolism. Biomolecules such as NADH, flavins, retinoids, cytochrome C and many others can now be non-invasively monitored. As metabolic dysregulation is common across the spectrum of diseases, this next-generation methodology has impact across a broad range of biomedical scenarios, including diagnostics of various health conditions such as neurodegeneration and cancer. Prof. Goldys will provide further examples from the area of reproductive medicine and ophthalmology, as well as fundamental biological science.

What You Will Learn:
• How to deeply probe native cell autofluorescence and obtain signatures of diagnostic value from biological image analysis

Who Should Attend:
• Experts in novel microscopies, developers of high end and also deployable imaging technologies including from the industry
• Clinical researchers and practitioners as well as biomedical researchers

Aug 5, 2020 06:00 PM in Eastern Time (US and Canada)

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