In this webinar hosted by the OSA Optical Trapping and Manipulation in Molecular and Cellular Biology Technical Group, Prof. Phil Jones will discuss his work on trapping and deformation of soft microscopic objects using optical tweezers.
The first example Prof. Jones will present in this webinar is the stretching of red blood cells in a dual optical tweezers. The cells are obtained from patients exhibiting a number of eye conditions that present with different symptoms. He determines the deformability (resistance to stretching) of the red blood cells and shows that a change in deformability is correlated with particular symptoms.
The second example is droplets of oil-in-water microemulsions, which can be re-shaped by optical forces. Prof. Jones implements a number of techniques to characterize the droplet interfacial tension including thermal fluctuations of the droplet surface, and the relaxation rate following deformation. He exploits the temperature sensitivity of the interfacial tension in the region of the phase inversion temperature to allow him to estimate the heating effect of optical tweezers.
What You Will Learn:
• The concept of optical tweezers
• How to apply optical tweezers for trapping and measurement of the deformability of soft materials
• Two exemplary materials: red blood cells and droplets of oil-in-water microemulsions
Who Should Attend:
• Physicists, biologists, chemists and engineers interested in optical trapping, biotechnology, structured light, biological physics, and biosensing research