Join the Therapeutic Laser Applications Technical Group for this webinar featuring Daniel Palanker from Stanford University discussing the mechanisms and applications of non-damaging retinal laser therapy.
Traditional panretinal photocoagulation aims at destruction of a significant fraction of photoreceptors in the peripheral retina to reduce the metabolic load on the diabetic retinal vasculature and thereby save the central vision by preventing neovascularization in the macula. However, grid photocoagulation in the macula never had any underlying rationale. We conjecture that the benefits of the laser therapy in the macula may result from thermal stimulation of the retinal cells rather than from their destruction. With this in mind, we established the response range of the retinal cells to hyperthermia below the damage threshold, using bioluminescent marker associated with heat-shock proteins upregulation. We also established a titration protocol to define the proper laser settings for non-damaging laser therapy in every patient.
Using this protocol, we demonstrated that the non-damaging retinal laser therapy is effective in treatment of Central Cerous Retinopathy and Macular Telangectasia, and its efficacy for treatment of the diabetic macular edema is being tested. The non-damaging approach may become a new paradigm in the retinal laser therapy, where the lack of tissue damage enables high-density treatment to boost its clinical efficacy, therapy in the fovea, and retreatments to manage chronic diseases.
Subject Matter Level: Intermediate - Assumes basic knowledge of the topic
What You Will Learn:
• Principles and mechanisms of the retinal laser therapy
• Modeling of the retinal hyperthermia
• Applications of non-damaging retinal laser therapy
Who Should Attend:
• Students, scientists and physicians interested in retinal laser therapy and learning about principles, practical aspects and novel capabilities of this method enabled by a non-damaging approach.